Cyth domain
WebOct 6, 2024 · CYTH is an ancient domain named by combining adenylyl cyclase and thiamine triphosphatase (ThTPase) (Iyer and Aravind, 2002). It was proposed that CYTH could be considered as a branch of TTM (Gong et al., 2006). However, the ThTPase and RNA triphosphatase activities were mainly found in mammals and yeast (S. cerevisiae). WebCYTH is an ancient enzymatic domain, and that a representative must have been present in the last uni-versal common ancestor (LUCA) of all extant life forms. It was proposed [4] that this enzymatic domain might play a central role at the interface between nucleotide and polyphosphate metabolism, but this role remained largely undefined: in ...
Cyth domain
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WebCYTH domains are likely to be domains specialized to bind nucleotides and other organic phosphates . The catalytic core of the CYTH domain is predicted to contain an … WebThe CYTH domains contains several nearly universally conserved charged residues that are likely to form the active site. The most prominent of these are an EXEXK motif associated with strand-1 of the domain, two basic residues in helix-2, a K at the end of strand 3, an E in strand 4, a basic residue in helix-4, a D at the end of strand 5 and ...
WebSep 5, 2013 · The CYTH-like phosphatase superfamily is an ancient gene family distributed across all biological kingdoms. The CYTH domain is named after its two founding … WebNational Center for Biotechnology Information
WebCYTH domain These sequences are functionally identified as members of the adenylate cyclase family, which catalyzes the conversion of ATP to 3',5'-cyclic … WebCYTH proteins make up a large superfamily that is conserved in all three domains of life. These enzymes have a triphosphate tunnel metalloenzyme (TTM) fold, which typically …
WebThis gene encodes a member of the cytohesin (CYTH) family, formerly known as the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. Cytohesin family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain.
WebLooking for the definition of CYTH? Find out what is the full meaning of CYTH on Abbreviations.com! 'Thompson Airport, Canada' is one option -- get in to view more @ … diamond with question mark symbolWebCYTH domain Provide feedback These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3',5'-cyclic AMP … cistern\u0027s h0WebDec 1, 2002 · CYTH enzymes are found in all three domains of life and can be traced back to the last common ancestor, which makes them appealing targets for studying protein … diamond with question markWebAssociated Domain (s): Death. Associated Deities: Pharasma. Replacement Power: The following granted power replaces the death’s embrace ability of the Death domain or the ward against death ability of the Repose domain. Psychopomps are a race of neutral outsiders (Pathfinder RPG Bestiary 4 217). Spirit Touch (Su): At 6th level, as a swift ... diamond with question mark symbol sqlWebsingular CYTH domain and one with a CYTH domain fused to a P-loop kinase domain (Iyer and Aravind, 2002). In Arabidopsis (Arabidopsis thaliana), there are threeTTMfamilymembers,AtTTM1,2,and3:AtTTM1 and 2 belong to the latter type, possessing a uridine kinase (UK) domain in addition to the CYTH domain, while … diamond with ruby necklaceWebThe SCOP classification for the CYTH domain family. Additional information, provided for both this family and the superfamily it belongs to, includes SUPERFAMILY links to … cistern\u0027s h2WebMar 17, 2024 · Abstract On the basis of bioinformatic evidence, we suspected that proteins with a CYTH ( Cy aB th iamine triphosphatase) domain and/or a CHAD ( c onserved h istidine α -helical d omain) motif might represent polyphosphate (polyP) granule-associated proteins. We found no evidence of polyP targeting by proteins with CYTH domains. cistern\\u0027s h2