Circrhobtb3
WebJun 2, 2024 · The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p Rising evidences bespeak that circular RNAs are indispensable in regulating cellular biological behaviors and engaging in diseases' occurrence. WebJan 13, 2024 · The circRHOBTB3 probe was incubated with streptavidin magnetic beads (Beaver, Suzhou, china) for 2 h to generate probe-coated beads, then incubated with cell lysates, followed by eluted with Trizol (Takara, japan), and qRT-PCR. for miR-654-3p pulled down, about 1 × 10 7 cells were collected, lysed, sonicated, and incubated with …
Circrhobtb3
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WebDec 1, 2024 · The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p Article Full-text available Jun 2024 Yihan Fu... WebFeb 11, 2024 · circRHOBTB3 is secreted outside of tumor cells and suppresses CRC cells in vitro and in vivo. (A) Expression of circRHOBTB3 in CRC or normal colonic epithelial …
WebJun 1, 2024 · Results: We identified circRHOBTB3 which is markedly downregulated in CRC tissues and cell lines. Furthermore, lower circRHOBTB3 levels were significantly …
WebMar 20, 2024 · CircRHOBTB3 interacted with the RNA-binding protein, IGF2BP3, to stabilize its expression in CC cells and is putatively transcriptionally regulated by NR1H4. WebFigure Legend Snippet: CircRHOBTB3 is down-regulated in EOC. A Schematic illustration showing the circularization of RHOBTB3 exon 6 and exon 7 forming circRHOBTB3. B Relative expression of circRHOBTB3 in OC cell lines compared with IOSE-80 was measured by qRT-PCR. C The existence of circRHOBTB3 was validated by RT–PCR …
WebcircRHOBTB3是通过宿主基因RHOBTB3的剪接和环化产生的。 作为Rho GTPase家族的ATPase，宿主基因RHOBTB3参与膜转运和蛋白酶体降解，可通过促进肾癌中HIF-α的蛋白酶体降解来抑制肿瘤生长。 先前的研究还表明circRHOBTB3在卵巢癌、胃癌、CRC和肝细胞癌（HCC）中是一种肿瘤抑制性circRNA。 然而，其环化模式和外泌体分泌途径尚不明 …
WebSep 9, 2024 · Chen C, Yu H, Han F, Lai X, Ye K, Lei S, et al. Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness. Mol Cancer. 2024;21:46. chin chin green tea passion fruitWebZestimate® Home Value: $329,501. 103 S Brownthrush Cir, Wichita, KS is a single family home that contains 2,848 sq ft and was built in 1994. It contains 4 bedrooms and 3 … chin chin hammondWebFeb 11, 2024 · circRHOBTB3 was produced by splicing and circularization of the host gene RHOBTB3. As a Rho GTPase-family ATPase, the host gene RHOBTB3 is involved in membrane transport [ 8, 9] and proteasomal degradation [ 10] and can inhibit tumor growth by promoting the proteasomal degradation of HIF-α in renal cancer [ 11 ]. chin chin henleyWebJan 13, 2024 · Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibiting gastric cancer growth Taken together, this study revealed that circRHOBTB3 might … grand buffet restaurant marysville waWebIn a first step, eight circRNAs (circATXN10, circCRIM1, circCSNK1G3, circGUCY1A2, more »... cLPP, circNEAT1, circRHOBTB3, and circSTIL) were identified as differentially expressed via a genome-wide circRNA-based microarray analysis of six PCa samples. Additional bioinformatics and literature data were applied for this selection process. chin chin hk company limitedWebApr 25, 2024 · Our previous RNA-seq dataset has identified a series of differentially expressed circRNAs including circNEIL3 and circRHOBTB3 in PDACs. These results suggested that circRNAs might be prominent prognostic markers for PDAC. chin chin hamburg saselWebFeb 11, 2024 · Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer Jiaxin Chen, Yizheng Wu, +9 authors Zhangfa Song Biology, Medicine Theranostics 2024 TLDR Findings indicate that circRHOBTB3 exerts suppressive effects on CRC aggressiveness through the … chin chin gwynneville